What fluconazole costs if you have no insurance

What fluconazole is for

MedlinePlus, a health site from the National Library of Medicine, says fluconazole treats fungal infections. These include yeast infections of the vagina, mouth, throat and esophagus, which is the tube that leads from the mouth to the stomach. It comes as a tablet or as a liquid that you take by mouth.

The Centers for Disease Control and Prevention, or CDC, says vaginal yeast infections are usually treated with an antifungal cream put inside the vagina. The other usual choice is a single dose of fluconazole taken by mouth. The CDC says the creams can be sold over the counter. It also says testing is recommended before you start treatment. Your clinician decides which treatment fits you, and this page cannot say.

What the tablets cost

We found no government list of counter prices for fluconazole. The closest real numbers come from Medicare, the federal health plan for people 65 and older and some younger people with disabilities. Its Part D plans are the ones that pay for prescriptions. The Centers for Medicare and Medicaid Services reports what those plans and their members spent on each drug.

For generic fluconazole in 2024, that spending averaged about $10.07 per prescription fill. The report counted more than 3.7 million fills from 13 different makers. The average fill held about 7 units, so most fills were small. This is not a cash price, but it shows that the medicine itself is inexpensive.

The second number comes from a national drug cost survey that Medicaid runs. It follows what pharmacies pay to buy a drug, so the price on your receipt will be higher. In the week of October 21, 2026, these were the survey prices for each tablet.

• The 50 mg tablet cost pharmacies about 19 cents.
• The 100 mg tablet cost about 22 cents.
• The 150 mg tablet cost about 51 cents.
• The 200 mg tablet cost about 37 cents.

Your prescriber picks the strength and the number of tablets. Your total is that number times the price per tablet, plus the pharmacy's fee. For a fill of one or two tablets, that fee is most of what you pay, so the counter price is often many times the survey price. The Ohio Department of Medicaid surveyed 2,198 pharmacies in 2022 and found that filling one prescription cost them about $9.46 on average. Calling around helps most on a small fill, because the fee is a bigger share of that price.

Even among generics, the cost differs from one maker to another. In the 2024 Medicare report, the larger generic makers averaged from about $8 to about $14 per fill. Prices at the counter vary from one pharmacy to the next, so a few phone calls can show a wide gap. Our guide on how to compare prescription prices shows what to ask.

When you call, give the pharmacy the strength and the number of tablets on your prescription. Ask for the cash price for that exact fill. Then ask whether the price changes if you pay without insurance, since some pharmacies list a different price for people who pay in cash. Write down each answer so you can compare stores.

Generic versus brand name

The same Medicare report lists the brand-name version separately. It averaged about $963 per fill in 2024, based on 348 fills. The brand fills were larger, with about 24 units each. Per unit, the brand cost about $24 and the generic cost about $2, where a unit is a tablet or a milliliter of liquid.

The Food and Drug Administration, or FDA, says a generic has the same active ingredient as the brand-name medicine. It also says that when several makers sell the same generic, competition typically lowers prices. Many makers sell generic fluconazole, and the pharmacy cost survey lists only generic tablets and liquid. Ask your pharmacist for the generic unless your prescriber has a reason to want the brand.

We found no program from the company that makes the brand-name version, and the generic is so inexpensive that one should not be needed.

The visit may cost more than the pill

Fluconazole tablets are a prescription medicine, so a clinician has to write the prescription. For many people without insurance, the visit costs more than the tablets. Ask for the price of the visit before you book.

• A community health center charges on a sliding scale, which means the fee depends on your income. Our guide on community health centers shows how to find one.
• A telehealth visit may cost less than an office visit. Our guide on telehealth without insurance explains what to expect.
• Urgent care is often the most costly option for a routine problem. Our guide on urgent care costs shows typical prices.
• A cash-pay doctor with a monthly membership may handle the visit for a known fee. Direct primary care usually costs $50 to $200 a month, and you can search for a cash-pay doctor near you.

You can find more ways to cut the cost of a medicine in our guide on prescriptions without insurance. We could not find a government source for the shelf price of over-the-counter yeast infection creams, so we do not quote one.

Safety points and when to get care right away

MedlinePlus says to tell your doctor and pharmacist about every medicine you take, because some medicines should not be taken with fluconazole. It also says to tell your doctor if you are pregnant or plan to become pregnant, since fluconazole may harm a baby in the womb. Please do not start, stop or change a medicine without asking your doctor or pharmacist.

MedlinePlus lists signs that need a call to your doctor right away or emergency treatment. They include yellow skin or eyes, dark urine, pale stools and pain in the upper right part of the stomach. Others are a rash, blistering or peeling skin, and swelling of the face or throat. Trouble breathing or swallowing and seizures are on the list too. In an emergency, call 911 or go to the nearest emergency room. In case of an overdose, call poison control at 1-800-222-1222. This page gives general information and is not medical advice.